Nimesulide Granules

Nimesulide Granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
Active ingredients: nimodipine. Indication: nimesulide granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea. Packaging: 1g / sack; 6, 8, 10 sacks / pack. Contact us for more information.

usage and consumption: oral, the goods only for adults only, a 50 mg to 100 mg daily twice postprandial taking. In accordance with the severity of the conditions and the needs of the patients can be increased to 0.2g, the second service.
elderly patients of the medication should strictly comply with the provisions of doctors. Doctors can reduce under appropriate in the circumstances listed above dosage.

Nimesulide has a potent Anti-Inflammatory action.It behaves as a competetive inhibitor of histamine release in-vivo and in-vitro, hence posseses antihistaminic and antiallergic properties.

Indications: Nimesulide is indicated in painful inflammatory conditions associated with musculoskeletal system, dysmenorrhoea, Thrombophlebitis, dental pain and in ENT inflammation. Absorption Well absorbed from GI tract following oral admin. Peak plasma levels:1-3 hours. With bid admin of 100 mg, steady-state is achieved within 24-36 hours.

Routes of Administration and Dosage: Oral dosage form in adults :100 mg b.i.d In children : 5 mg/kg/day in 2 or 3 divided doses.

Nimesulide for instant pain relief

Pain relief drug nimesulide which shows the instant pain relief from acute pain (short-term pain)within 15 minitues of drug intake for the acute pain.

Nimesulide is a prescription-only drug and must be prescribed by a licensed physician after careful evaluation of the patient’s characteristics and needs.

It must be used under supervision by a doctor in accordance with the approved indications and in compliance with the recommendations .The overall safety profile of nimesulide is in line with that of all other NSAIDs. As with all drugs, it must be used in the most appropriate way to guarantee its best therapeutic value.

Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, it is observed that the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic in action.

Nimesulide Analgesic action and Antipyretic properties

Nimesulide Analgesic action and Antipyretic properties

Nimesulide drug for pain relief has a relatively rapid onset of the analgesic action for the patients suffering from acute pain which shows meaningful reductions observed within 15 minutes from drug intake.

Nimesulide is a prescription-only drug and must be prescribed by a licensed physician after careful evaluation of the patient’s characteristics and needs.
As per the recent evaluations on the safety profile of nimesulide confirms that nimesulide has a favourable benefit/risk profile in the approved indications.

Nimesulide shows multifactorial mode of action for the treatment of for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide tablet has great analgesic and antipyretic properties which is nothing but relief from pain and reduction of body temperature.

The overall safety profile of nimesulide is in line with that of all other NSAIDs. As with all drugs, it must be used in the most appropriate way to guarantee its best therapeutic value.

As for other NSAIDs the use of Nimesulide is preffered for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea. The efficacy of Nimesulide was consistently superior to placebo with its particularly rapid onset action.

Nimesulide tablet purpose

NSAIDs prescribed painkiller drug- Nimesulide tablet is used for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide also has superior gastrointestinal safety as compared to other NSAIDs.

NImesulide is available in the dosage of 100 mgs for tablets, 100 mg for granules for oral suspension, 200mg for suppositories and 3% of gel.

The prescribed duration for the tablet to use is15 days and the dosage to be used is 100mgs.

The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

Additionally it also helps to reduce cancer and heart problem. It is also used for dry skin, to improve skin-tone,and to increase energy,

Nimesulide tablet prevents cancer by inhibiting the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms.

Nimesulide, a wide prescribed medication analgesic drug belongs to BCS category II and exhibit low and variable oral bioavailability. It posses properties of anti-inflammatory, analgesic, antipyretic and antihistaminic. It has a particularly good profile to support in terms of gastrointestinal tolerability.

Nimesulide treatment for acute pain

Nimesulide tablet is a prescription anti-inflammatory drug used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Original nimesulide was developped by Helsinn Healthcare and is marketed world-wide through a network of selected international partners.

Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, it is observed that the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic in action.

The rapid action shows the immediate relief within the 15 min from the drug intake for the acute pain.

The maximum duration and dose of a treatment course with nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.

Nimesulide should only be prescribed as second line treatment. The decision to prescribe nimesulide should be based on assessment of the individual patient’s overall risks.

Nimesulide dosage to reduce pain

Nimesulide treats post-traumatic inflammation, acute musculoskeletal disorders and osteoarthritis (joint pains).
It is available with the dosage of 100 mg for the tablets, and 100 mg for granules for oral suspension, 200 mg for the suppositories and 3% of gel.
Nimesulide tablet is recommended for the shortest duration. The maximum duration and dose of a treatment course with nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.
Non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor – Nimesulide has multi factorial approach for the treatment of for the treatment of post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.
The maximum duration recommended to be used is 15 days and dose required for the treatment 100 mg twice a day, to minimize the risk of hepatotoxicity.

It has low gastro-intestinal and renal toxicity. with analgesic and antipyretic properties.

Nimesulide Painkiller Drug

Nimesulide Painkiller Tablet

Nimesulide is used in giving relief from acute pain associated with rheumatoid arthritis, osteoarthritis and primary dysmenorrhoea in adolescents and adults.

The drug is also an effective antipyretic and used to treat headaches and flu. It is also used in treating inflammatory conditions in humans and pain caused by arthritis or severe injury.

Nimesulide is a popular NSAID and available in various forms including tablets, suppositories, water-soluble powders, and topical gels.

Working of Nimesulide:

It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation

Nimesulide Dosage:

Adults: 100 mg twice daily

Children: 5mg/kg of body weight in 2 or 3 divided doses.

The maximum duration of a treatment course with Nimesulide is 15 days

Nimesulide Uses

Nimesulide Tablet Uses

Nimesulide medication is a non-steroidal anti-inflammatory drug with analgesic and antyperetic properties, prescribed for painful inflammatory conditions, back pain, dysmenorrhea and etc.

The usual dosage of Nimesulide is 100mg twice a day. For children it should be taken 5mg/kg of body weight in 2 or 3 divided doses

Nimesulide is used to reduce:

1. Osteoarthritis
2. Low back Pain
3. Sports injury
4. Dental pain
5. Moderate pain & fever
6. Dysmenorrhe                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
   Nimesulide Drug uses: 
   
7. Nimesulide has less gastrointestinal adverse effects than other NSAIDs.
8. It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
9. Rapid onset of action within 15 minutes
10. Rapidly relieves pain in arthritis
11. Its multifactorial mode of action gives it a unique and broad action on inflammatory.
12. Nimesulide is also safe in sensitive asthmatic patients.
13. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
14. Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities.

Nimesulide tablet for headache

Postoperative headache may be caused by hypoglycemia and/or dehydration due to prolonged fasting, caffeine withdrawal, anxiety, and can be associated with preexisting migraine or headache.

NSAIDs- Nimesulide, is the first line pharmacological approaches to postoperative headache.

Nimesulide gives rapid onset of pharmacological action, good pain relief and stable effect for many hours is an ideal drug for postoperative headache with no contraindications.

It is also used for the treatment of acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders, acute pain, osteoarthritis, primarydysmenorrhoea.

Nimesulide is available in various forms including tablets, suppositories, water-soluble powders, and topical gels.

The maximum duration of a treatment course with Nimesulide is 15 days.

Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.

Nimesulide Painkiller Tablet

Nimesulide Painkiller Tablet 

Nimesulide is used in giving relief from acute pain associated with rheumatoid arthritis, osteoarthritis and primary dysmenorrhoea in adolescents and adults.

The drug is also an effective antipyretic and used to treat headaches and flu. It is also used in treating inflammatory conditions in humans and pain caused by arthritis or severe injury.

Nimesulide is a popular NSAID and available in various forms including tablets, suppositories, water-soluble powders, and topical gels.


Working of Nimesulide:

It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation 


Nimesulide Dosage:

Adults: 100 mg twice daily
Children: 5mg/kg of body weight in 2 or 3 divided doses.

The minimum effective dose should be used for the shortest duration to reduce the undesirable effects.

The maximum duration of a treatment course with Nimesulide is 15 days.

Nimesulide benefits

NSAIDs prescribed painkiller drug- Nimesulide tablet is used for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

Nimesulide tablet was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide.

It is available in a variety of forms: tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide also has superior gastrointestinal safety as compared to other NSAIDs.

Nimesulide is a non-steroidal anti-inflammatory drug. It is used for the treatment of:

• Acute (short-term) pain
• Osteoarthritis (Joint pains)
• Primary Dysmenorrhoea (period pains)

Nimesulide is also used to:

• Increase in energy
• Improve skin tone
• Heart disease
• Dry skin

Nimesulide Dosage:

Adults: 100 mg twice daily
Children: 5mg/kg of body weight in 2 or 3 divided doses.

The minimum effective dose should be used for the shortest duration to reduce the undesirable effects.

The maximum duration of a treatment course with Nimesulide is 15 days.

Nimesulide Gel

Nimesulide Gel Uses

Standard

Nimesulide is available in various forms including tablets, suppositories, water-soluble powders, and topical gels.

Original Nimesulide is commercially available as tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).


Nimesulide Gel (Nimesulide/Methyl Salicylate/Menthol/Capsaicin) is used to treat chronic and acute musculoskeletal disorders such as soft tissue injuries or non-articular rheumatic disorders, including discomfort in the muscles, tendonitis, back pain/ache, arthritis, tenosynovitis sprains, or strains.


Dosage and Administration
Nimesulide Gel is apply to the affected area, rubbing in a thin layer of the gel 2 to 4 times every day. For best results, wash the application area beforehand to clean away any oil, grease, or bacteria, allowing the gel to absorb more easily.


Nimesulide is available in assortment of structures like as tablets and syrup for oral organization and gels for topical application.


The anti-inflammatory activity of topically applied Nimesulide gel demonstrations particularly on cyclo-oxygenase-2 which applies less gastrointestinal antagonistic impacts than different NSAIDs.

Nimesulide BP

Nimesulide BP

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory pain killer drug(NSAID) prescribed for treatment of acute pain, Primary dysmennorhea and degenerative joint disease.

This medicine has potent analgesic, anti pyretic and anti-inflammatory activity on oral & rectal administration.

Nimesulide BP 100mg prevents the release of prostaglandins which is responsible for inflammation, pain & fever.

Nimesulide is a selective inhibitor of prostaglandin synthesis but appears to exert its therapeutic effect by a variety of other mechanisms like inhibition of platelet-activating factor (PAF), tumour necrosis factor-alpha (TNF alpha,) Proteinase & histamine etc.

 Nimesulide is Indicated in reducing pain, fever and inflammatory symptoms of:

• Chronic arthritis
• Osteo arthritis
• Otorhinolary diseases
• Soft tissues and oral cavity inflammation
• Dysmenorrhoea
• Thrombosis
• Urogenital disease
• Postoperative pain states
• Sports injuries

Nimesulide Brands in India

Nimesulide Brands in India

NSAID’s tablet Nimesulide is a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II which is required for the quick treatment of severe muscular pains and inflammatory problems.

NSAID’s tablet Nimesulide is been available since 1985 and sanction with assorted trade names in worldwide in abundance of 50 countries.

Nimesulide is distributed world-wide through a network of selected international partners. 

Different trademarks of Nimesulide are: 

For Oral Use: Sulide, Nimalox, Nimesil, Nimulid, Nicip (India),, Nimcap, Nise, Sulidene and Zolan, Pain Lock(VIP Pharma India ), Nilden (Mexico),

Why Nimesulide Drugs are Used?

The main purpose of using Nimesulide are:

• To treat acute pain
• To treat osteoarthritis
• To treat primary dysmenorrhoea in adolescents and adults above 12 years old.

Nimesulide tablet incorporates:

• Fast results
• Helpful and supportive
• No feature impacts
• Fast and quick effects

Nimesulide Solubility

Solubility of Nimesulide was studied using different cosolvent mixtures and various classes of non-ionic surfactant. Solubility increased drastically (>70 mg/rnl) when polyethylene glycol 300 and polyethylene glycol 400 were used as solvents.

The quick dissolving tablets of Nimesulide contains superdisintegrants, that accelerates the disintegration of tablets by virtue of their ability to soak up great deal of water once exposed to binary compound surroundings.

Nimesulide is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, Nimesulide should first be dissolved in ethanol and then diluted with the aqueous buffer of choice. Nimesulide has a solubility of approximately

<200 μg/ml in a 10% DMSO in PBS (pH 7.2) solution using this method.

NSAID drug NImesulide has proven benefits in the treatment of Acute (short term) pain, Painful osteoarthritis (Swelling in the joints) and Primary dysmennorhea (Period Pains).
Nimesulide is available in various forms like Nimesulide Tablets, Nimesulide Powder, Nimesulide Gell, suppositories etc.
Nimesulide is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).

nimesulide is an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity.As for other NSAIDs the use of nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea.

Nimesulide Drug Uses

• Nimesulide has less gastrointestinal adverse effects than other NSAIDs.
• It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory.
• Nimesulide is also safe in sensitive asthmatic patients.
• It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
• Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities.
  Nimesulide does not have significant gastroduodenal side effects.
  It has superior gastrointestinal safety as compared to other NSAIDs.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.
  It has proven benefits in the treatment of Acute (short term) pain, Painful osteoarthritis (Swelling in the joints) and Primary dysmennorhea ( Period Pains).
  To treat acute pain
  To treat osteoarthritis
  To treat primary dysmenorrhoea in adolescents and adults above 12 years old.
  Increasing Energy
  Improving Skin Tone.

Nimesulide Structure

Nimesulide Structure

Nimesulide is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It is available in more than 50 countries worldwide.

Features:

• Amongst most effective yet gastro friendly
• Non steroidal anti inflammatory drug (NSAID)
• Nimesulide targets COX-2 an enzyme responsible for inflammation & pain.

Uses of Nimesulide:

1. Nimesulide tablet has excellent gastrointestinal safety in comparison to other medication.
2. Rapid onset of action within 15 minutes
3. Rapidly relieves pain in arthritis

Nimesulide Tablet Uses

Nimesulide Tablet Uses

Nimesulide medication is a non-steroidal anti-inflammatory drug with analgesic and antyperetic properties, prescribed for painful inflammatory conditions, back pain, dysmenorrhea and etc.

The usual dosage of Nimesulide is 100mg twice a day. For children it should be taken 5mg/kg of body weight in 2 or 3 divided doses

Nimesulide is used to reduce:

1. Osteoarthritis
2. Low back Pain
3. Sports injury
4. Dental pain
5. Moderate pain & fever
6. Dysmenorrhea

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.

Nimesulide drug interactions

Nimesulide is a prescribed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults.

it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.

Nimesulide is also available in the form of dissolving tablets, granules for oral suspension, and Gel. The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous Environment.

Major interactions involving interference with drug metabolism have not been described with Nimesulide.

A marginal decrease in plasma theophylline levels (without changes in respiratory function tests) has been described after addition of Nimesulide to chronic theophylline therapy. Nimesulide is available in the market with the dosage of 100Mg.

Nimesulide composition

Nimesulide is a non-steroidal anti-inflammatory agent that is widely used in the treatment of inflammatory pain.The efficacy and tolerability of nimesulide was consistently superior to placebo.

Nimesulide tablet undergoes extensive biotransformation and has a relatively rapid onset of action, with meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.

The drug belongs to the class II of Biopharmaceutical Classification System (low solubility, high permeability) and therefore, absorption of this drug is limited by its dissolution.

 Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-2 an enzyme responsible for inflammation & pain.

The nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.

This medication is for the most part used as an issue of the treatment of inflammatory torment and also used for postoperative trauma, sports injuries, acute musculoskeletal disorders.

Uses of Nimesulide:

• Rapid onset of action within 15 minutes
• Rapidly relieves pain in arthritis

The nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.

This medication is for the most part used as an issue of the treatment of inflammatory torment and also used for postoperative trauma, sports injuries, acute musculoskeletal disorders

Nimesulide Structure

Nimesulide Structure

Nimesulide is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It is available in more than 50 countries worldwide.

Features:

• Amongst most effective yet gastro friendly
• Non steroidal anti inflammatory drug (NSAID)
• Nimesulide targets COX-2 an enzyme responsible for inflammation & pain.

Uses of Nimesulide:

1. Nimesulide tablet has excellent gastrointestinal safety in comparison to other medication.
2. Rapid onset of action within 15 minutes
3. Rapidly relieves pain in arthritis

Ninesulide Tablet uses

Nimesulide Tablet Uses

Nimesulide medication is a non-steroidal anti-inflammatory drug with analgesic and antyperetic properties, prescribed for painful inflammatory conditions, back pain, dysmenorrhea and etc.

The usual dosage of Nimesulide is 100mg twice a day. For children it should be taken 5mg/kg of body weight in 2 or 3 divided doses

Nimesulide is used to reduce:

1. Osteoarthritis
2. Low back Pain
3. Sports injury
4. Dental pain
5. Moderate pain & fever
6. Dysmenorrhea

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.

Precautions:

Women should use the drug with caution during lactation; Nimesulide is contraindicated during pregnancy.

Nimesulide for instant pain relief

Pain relief drug nimesulide which shows the instant pain relief from acute pain (short-term pain)within 15 minitues of drug intake

Nimesulide is a prescription-only drug and must be prescribed by a licensed physician after careful evaluation of the patient’s characteristics and needs.
Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.
In these studies, it is observed that the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic in action.

The rapid action shows the immediate relief within the 15 min from the drug intake for the acute pain.

It must be used under supervision by a doctor in accordance with the approved indications and in compliance with the recommendations .The overall safety profile of nimesulide is in line with that of all other NSAIDs. As with all drugs, it must be used in the most appropriate way to guarantee its best therapeutic value.

Nimesulide Tablet Dose

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) with analgesic (painrelief) and antipyretic(fever-reducing) effects.

Indications:

Nimesulide is mostly used for treatment of short-term pain(Acute), joint pain (osteoarthritis), period pains (Primary dysmennorhea), Chronic pains (long-term) and many.

Nimesulide Dosage:

• Adults: 100 mg twice daily
• Children: 5mg/kg of body weight in 2 or 3 divided doses.
• Oral
  Dysmenorrhoea
  Adult: 100 mg bid limited to a max of 15 days.
• Oral
  Osteoarthritis
  Adult: 100 mg bid limited to a max of 15 days.
• Oral
  Postoperative pain
  Adult: 100 mg bid limited to a max of 15 days.
• Oral
  Acute pain
  Adult: 100 mg bid limited to a max of 15 days.

The maximum duration and dose of a treatment course with Nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.

Uses of Nimesulide:

• Rapid onset of action within 15 minutes
• Rapidly relieves pain in arthritis(joints).
• Nimesulide has superior gastrointestinal safety as compared to other NSAIDs.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

The onset of action of nimesulide is faster and also has a potent and long lasting anti-pyretic affect.

Nimesulide tablet dissolution

The most commonly prescribed NSAID's drug - Nimesulide for the treatment of various inflammatory conditions such as tonsillitis, pharyngitis, stomatitis, rheumatoid arthritis, osteoarthritis, low back pain etc.,

The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous environment.

Nimesulide is also well tolerated by asthmatic patients

Nimesulide is available in various forms like Nimesulide Tablets, Nimesulide Powder, Nimesulide Gel, suppositories etc.

Nimesulide is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).

Nimesulide is an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity.

The prescription of a drug is appropriate when the benefit it is able to provide to a specific patient outweigh the risks associated with its use. A careful evaluation of individual risk factors is therefore of crucial importance.

As for different NSAIDs the employment of Nimesulide is usually recommended for the shortest length necessary to regulate symptoms in patients with acute pain or primary dysmenorrhoea

The prescription of a drug is acceptable once the profit it’s ready to offer to a selected patient outweigh the risks related to its use. A careful analysis of individual risk factors is so of crucial importance.

As for different NSAIDs the employment of Nimesulide is usually recommended for the shortest length necessary to regulate symptoms in patients with acute pain or primary dysmenorrhoea.

Nimesulide tablet indications

Anti-inflammatory Analgesics tablet – Nimesulide is very much required for the quick treatment of severe muscular pains and inflammatory problems. Nimesulide tablets is available in different countries in the world.

Nimesulide is indicated in painful inflammatory conditions associated with musculoskeletal system,
dysmenorrhoea, Thrombophlebitis, dental pain and in ENT inflammation.

Features:

• Desirable results
• Helpful and beneficial
• No side effects
• Fast and quick effects

Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by

the clinical situation.

This medicine is for the most part used as an issue of the treatment of inflammatory torment and also used for postoperative trauma,sport injuries, acute musculoskeletal disorders

Dosage:

 

Tablets or Granules: 100 mg twice a day after meals

400 mg nimesulide-beta-cyclodextrin Tablets or Granules: 400 mg (= 100 mg nimesulide)

twice a day after meals

Suppositories: 200 mg twice a day

Indications:

Osteoarthritis

Low back pain

Sports injury

Dental pain

Moderative pain &fever

dysmenorrhea.

Nimesulide 100mg Tablet

Nimesulide 100mg Therapeutic indications:

• Treatment of acute pain
• Symptomatic treatment of painful osteoarthritis (pain and swelling of joints)
• Primary dysmenorrhoea.

Nimesulide is available in the market in various forms including tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

How It Works:

Nimesulide belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the production of prostaglandins (a chemical associated with pain) thereby relieving pain and inflammation.

The maximum duration of a treatment course with Nimesulide is 15 days. Nimesulide 100mg Tablets/granules should be used for the shortest possible duration.

Nimesulide 100mg is Indicated in reducing pain, fever and inflammatory symptoms of:

• Chronic arthritis (long-term disease)
• Osteo arthritis (joint-pains)
• Otorhinolary diseases (ear, nose and throat)
• Soft tissues and oral cavity inflammation
• Dysmenorrhoea (period pains)
• Thrombosis (clotting of blood in circulatory system)
• Urogenital disease (urinary and genital organs.)
• Postoperative pain states (pain after surgery)
• Sports injuries

Nimesulide 100mg is also proved to be safe in asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis (inflammation of mucous membrane inside nose), cold.

Nimesulide brands in india

NSAID’s tablet Nimesulide is a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II which is required for the quick treatment of severe muscular pains and inflammatory problems.

NSAID’s tablet Nimesulide is been available since 1985 and sanction with assorted trade names in worldwide in abundance of 50 countries.

Nimesulide is distributed world-wide through a network of selected international partners. 

Different trademarks of Nimesulide are: 

For Oral Use: Sulide, Nimalox, Nimesil, Nimulid, Nicip (India),, Nimcap, Nise, Sulidene and Zolan, Pain Lock(VIP Pharma India ), Nilden (Mexico)

The most powerfull painkiller NSAIDs tablet Nimesulide is been available since 1985 and authorised in worldwide over 50 countries.

It has superior gastrointestinal safety as compared to other NSAIDs.

It is available in various forms apart from tablets such as in the form of Gell, powder, and suppositories. It’s also available in several trademarks.

Nimesulide brands such as Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.

Nimulid is also obtaining in the form of gel.

The most powerfull painkiller NSAIDs tablet Nimesulide is been available since 1985 and authorised in worldwide over 50 countries.

It has superior gastrointestinal safety as compared to other NSAIDs.

It is available in various forms apart from tablets such as in the form of Gell, powder, and suppositories. It’s also available in several trademarks.

Nimesulide brands such as Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.

Nimulid is also obtaining in the form of gel.

Prescribe pain killer drug

The most prescribed anti-inflamatory drug Nimesulide was first developed by Helsinn Healthcare and is marketed world-wide.

NImesulide is available in the form of tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

The anti-inflammatory drug mechanism of Nimesulide should only be prescribed as second line treatment. It provides the fast onset of the analgesic action.

The rapid onset of the analgesic action is crucial for the patients with acute pain and also in case of treatment with systemic NSAIDs

The harmonized indications in the EU are acute pain, primary dysmenorrhoea. The dosage of Nimesulide ought to be used is 100 mg twice daily, the duration prescribed is 15 days to minimize the risk of hepatotoxicity.

The drug must be used under supervision by a licensed physician in accordance with the approved indications. Prescription of the Nimesulide must be based on assessment of the patients’ characteristics and needs. Nimesulide is contraindicated in children below 12 years and in patients suffering from liver problems.

Nimesulide for instant pain relief

Pain relief drug nimesulide which shows the instant pain relief from acute pain (short-term pain)within 15 minitues of drug intake

Nimesulide is a prescription-only drug and must be prescribed by a licensed physician after careful evaluation of the patient’s characteristics and needs.

It must be used under supervision by a doctor in accordance with the approved indications and in compliance with the recommendations .The overall safety profile of nimesulide is in line with that of all other NSAIDs. As with all drugs, it must be used in the most appropriate way to guarantee its best therapeutic value.

Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, it is observed that the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic in action.

The rapid action shows the immediate relief within the 15 min from the drug intake for the acute pain.

Nimesulide Gel

Nimesulide is a non-steroidal anti-inflammatory (NSAID) drug which has been found to be useful in the treatment of fever.Clinical studies of Nimesulide in treating children with fever have been carried out. In the children receiving Nimesulide, it took 8.6h to reach normal temperature.  The mean decrease in temperature for each cycle was slightly higher for the Nimesulide group. The drugs were well tolerated by the children.Nonsteroidal anti-inflammatory drugs (NSAIDs) are the mainstay of treatment in pain. Various fixed dose combinations of NSAIDs are available in the market, particularly those of paracetamol and ibuprofen.

No side effects were reported in any child. The result showed that Nimesulide acted more rapidly in bringing down the temperature to normal.

Nimesulide appears to exert its effects also through a variety of other mechanisms and involves interference with the production action of mediators other than prostaglandins such as enzymes, toxic oxygen derivatives, cytokines, platelet activating factor and histamine.

The anti-inflammatory activity of topically applied Nimesulide gel commonly used in the management of Musculoskeletal injuries.

Nimesulide gel possesses higher anti-inflammatory activity compared to other gel’s.

The superior analgesic activity of Nimesulide transdermal gel has reported good results in terms of decreasing pain and improved functions in musculoskeletal conditions after topical application.

Nimesulide transdermal gel is a novel hydroalcoholic microcarrier based drug delivery system with penetration enhancer.

Treatment:

Nimesulide gel is demonstrated for an assortment of conditions depicted by anguish, irritation and strength, for instance, osteoarthritis, periarthritis, post-traumatic or extreme musculoskeletal issue including tendinitis, tenosynovitis, sprains, strains and low back torment. It Functions via limiting particular nerve inspirations sent from the edge to your central system.