Showing posts with label Nimesulide formulation. Show all posts
Showing posts with label Nimesulide formulation. Show all posts

Thursday, December 10, 2015

Nimesulide Efficacy

The efficacy of nimesulide (100mg twice daily) was compared with that of naproxen (500mg twice daily) in 53 adult patients with nonbacterial acute inflammation of the ear, nose or throat in a double-blind phase III clinical investigation. Both drugs were administered orally after meals for a mean duration of 8.7 days.
In this setting, nimesulide was associated with relief of pain and inflammatory signs (exudation and swelling). Indeed, treatment with nimesulide led to clinical improvement superior to that obtained with naproxen in terms of both rapidity of action and improvement of the symptoms at the end of therapy. Nimesulide therapy was also very well tolerated and no patient reported an adverse event. In contrast, 2 naproxen-treated patients reported episodic gastralgia of moderate intensity.
Nimesulide's therapeutic value in effectively and rapidly controlling inflammation and pain is supported by significant clinical evidence.
Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, the efficacy of nimesulide was consistently superior to placebo and at least comparable, or in some cases superior, to that observed for the reference drugs, with a particularly fast onset of the analgesic action.

Nimesulide posses analgesic properties with multifactorial mode of action for the treatment of musculoskeletal system, dysmenorrhoea, and acute pain.
The abilities of NSAID’s drug nimesulide to inhibit COX-2 preferentially and to exert other novel anti-inflammatory actions are consistent with good efficacy and safety with highly effective in reducing pain, inflammation and also helps in better penetration of the antibiotics.

It also undergoes extensive biotransformation. The recent study on the basis of analgesic activity of Nimesulide has proved that it has a quicker onset which shows relief from pain relief and inflammation within 15 minutes from drug intake.
Nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea.



Friday, December 4, 2015

Nimesulide tablet chemical formula


Nimesulide, a wide prescribed medication analgesic drug belongs to BCS category II and exhibit low and variable oral bioavailability.
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a selective Cox-2 anti-inflammatory drug drug. This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatorydrug. It belongs to selective COX-2inhibitors, with a potent analgesic activity.
it’s indicated as second line treatment for acute pain, symptomatic treatment of painful degenerative joint disease and first dysmenorrhoea.
It’s conjointly used for the treatment of skin-tone, Heart diseases and dry skin.
Features include :
  • Fascinating results
  • Useful and helpful
  • No facet effects
  • Quick and fast effects

Usage of Nimesulide 100mg- pill :
  • Analgesic and antipyretic.
  • Rheumatic inflammatory disease, degenerative joint disease, alternative chronic joint disorders treatment
  • Musculo skeletal disorders treatment
  • Thrombophlebitis.
  • Improves skintone
  • Heart Diseases
  • Dry Skin
  • Cancer treatment

Nimesulide formulation

Nimesulide, a wide endorsed medicine pain relieving drug fits in with BCS classification II and show low and variable oral bioavailability. 

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.

It's conjointly utilized for the treatment of skin-tone, Heart illnesses and dry skin.

Nimesulide tablet features incorporate :
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Use of Nimesulide 100mg- pill :
  • Pain relieving and antipyretic.
  • Rheumatic inflammatory sickness, degenerative joint ailment, elective perpetual joint issue treatment
  • Musculo skeletal issue treatment
  • Thrombophlebitis.
  • Enhances skintone
  • Heart Diseases
  • Dry Skin
  • Malignancy treatment

Thursday, November 19, 2015

Nimesulide in treatment of dengue


Nimesulide is prescribed for the treatment of Dengue. Dengue i s the most rapidly spreading mosquito-borne viral disease in the world it is an acute febrile viral disease frequently presenting with headaches, bone or joint and muscular pains, rash and leukopenia as symptoms.
Nimesulide is COX-2 selective non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic propertiesNimesulide is available with the dosage of 100 mg for tablets, 100 mg for granules for oral suspension, 200mg for suppositories and 3% of gel.
Nimesulide Tablet is used for:
  • Rapid onset of action within 15 minutes
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms

Wednesday, November 18, 2015

Nimesulide Formulation


Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compound, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatory drug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.
its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

Wednesday, September 30, 2015

Nimesulide Formulation and its purpose

Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatory drug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

Additionally it also helps to reduce cancer and heart problem. It is also used for dry skin, to improve skin-tone,and to increase energy

Its shown as second line treatment for acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.

Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities.

Wednesday, December 31, 2014

Nimesulide Tablet Formulation

Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.
 
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment. 
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

Sunday, December 7, 2014

Nimesulide Tablet Formulation and its Advantages

Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.
 
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment. 
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

Friday, November 21, 2014

Nimesulide Tablet Formulation

Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.
 
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment. 
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

Thursday, October 30, 2014

Nimesulide Formulation and features

Nimesulide, a wide endorsed medicine pain relieving drug fits in with BCS classification II and show low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.

It's conjointly utilized for the treatment of skin-tone, Heart illnesses and dry skin.

Nimesulide tablet features incorporate :
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Use of Nimesulide 100mg- pill :
  • Pain relieving and antipyretic.
  • Rheumatic inflammatory sickness, degenerative joint ailment, elective perpetual joint issue treatment
  • Musculo skeletal issue treatment
  • Thrombophlebitis.
  • Enhances skintone
  • Heart Diseases
  • Dry Skin
  • Malignancy treatment