Nise pain relief tablet

''Nise'' tablet is a trademark for the drug ''Nimesulide'' which is non-steroidal anti-inflammatory drug (NSAID)
  with analgesic and antipyretic properties.

  It is used for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

 Nimesulide drug was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available     in more than 50 countries worldwide with different trademarks such as Nise, Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Sulidene, and Zolan etc.

It has superior gastrointestinal safety as compared to other NSAIDs.

Nise tablet also shows rapid analgesic activity which gives reductions for the pain within 15 minutes from drug intake.

It must be used under supervision by a doctor in accordance with the approved indications and in compliance with the recommendations.

 

Nise medicine has the rapid onset of analgesic action which shows the immediate relief within the 15 min from the drug intake for the acute pain.

prescribed painkiller drug-nimesulide

The most prescribed anti-inflamatory drug Nimesulide was first developed by Helsinn Healthcare and is marketed world-wide.

NImesulide is available in the form of tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

The anti-inflammatory drug mechanism of Nimesulide should only be prescribed as second line treatment. It provides the fast onset of the analgesic action.

The rapid onset of the analgesic action is crucial for the patients with acute pain and also in case of treatment with systemic NSAIDs

The harmonized indications in the EU are acute pain, primary dysmenorrhoea. The dosage of Nimesulide ought to be used is 100 mg twice daily, the duration prescribed is 15 days to minimize the risk of hepatotoxicity.

The drug must be used under supervision by a licensed physician in accordance with the approved indications. Prescription of the Nimesulide must be based on assessment of the patients’ characteristics and needs.

Nimesulide is contraindicated in children below 12 years and in patients suffering from liver problems.

Nimesulide efficay in pain

The abilities of NSAID’s drug nimesulide to inhibit COX-2 preferentially and to exert other novel anti-inflammatory actions are consistent with good efficacy and safety with highly effective in reducing pain, inflammation and also helps in better penetration of the antibiotics.

Nimesulide posses analgesic properties with multifactorial mode of action for the treatment of musculoskeletal system, dysmenorrhoea, and acute pain .

It also undergoes extensive biotransformation. The recent study on the basis of analgesic activity of nimesulide has proved that Nimesulide had a quicker onset which shows relief from pain relief and inflammation within 15 minutes from drug intake.

Nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea.

Nimesulide is available in distinctive brands, for instance, Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene, Zolan and etc.

Nimesulide tablet for cancer treatment

Cancer, also known as a malignant tumour or malignant neoplasm, is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Cyclooxygenase-2 (COX-2) inhibitor Nimesulide inhibits the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms, which makes it a good lead compound for anti-cancer drug development.

There are more than 100 types of cancer, including breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma. Symptoms vary depending on the type.

A series of new nimesulide analogs were synthesized based on the structure–function analysis generated previously. It displayed very potent anti-cancer activity.

significantly suppresses the growth of multiple cancer. By usng Nimesulide the sizes of the colon carcinomas were also decreased.

Pharmacokinetic studies demonstrate the good bioavailability of the compound. A set of non-COX-2 active Nimesulide anti-cancer derivatives were synthesized. It works as a good lead compound for anti-cancer drug development

Nimesulide granules

Nimesulide Granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

Active ingredients: nimodipine. Indication: nimesulide granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Packaging: 1g / sack; 6, 8, 10 sacks / pack. Contact us for more information.

usage and consumption: oral, the goods only for adults only, a 50 mg to 100 mg daily twice postprandial taking. In accordance with the severity of the conditions and the needs of the patients can be increased to 0.2g, the second service.

elderly patients of the medication should strictly comply with the provisions of doctors. Doctors can reduce under appropriate in the circumstances listed above dosage.

Nimesulide pill

A non-steroidal anti-inflammatory most prescribed drug – Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.

This trademark also has several products by the brand name of Nimulid, Nise.

Popular NSAID drug Nimesulide is available in various forms including tablets, suppositories, soluble powders, and topical gels.

Major interactions involving interference with drug metabolism have not been described with Nimesulide.

Nimesulide is a leading NSAID’S srug with analgesic, antipyretic and anti-inflammatory Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .

Nimesulide Tablet shows the result from pain within 15min from the drug intake

Nimesulide medicine uses

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor. It has become a leading NSAID in over 50 countries worldwide.

Nimesulide tablet is used for the treatment of osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders

Nimesulide a specific Cox-2 anti-inflammatory medication which have been turned out to be fundamentally more suitable in giving symptomatic alleviation for intense agony, symptomatic treatment of horrifying degenerative joint sickness and first dysmenorrhoea.

The European Medicines Agency has finished an review of the security and viability of solutions containing Nimesulide (capsules, tablets, suppositories and powder or granules for oral suspension).

Usage of Nimesulide 100mg- Tablet:

Nimesulide has less gastrointestinal adverse effects than other NSAIDs
It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
Its multifactorial mode of action gives it a unique and broad action on inflammatory.
Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.

Nimesulide synthesis

Nimesulide is a COX-2 selective drug which has the properties of antiinflammatory and antihistaminic, it also possesses analgesic properties.

Apart for the treatment of acute pain, osteoarthritis and primary dysmenorrhoea. Nimesulide is also being widely used for anticancer and antiviral agents.

A variety of new nimesulide derivatives were synthesized through incorporation of a 5-LOX pharmacophore into Nimesulide followed with some structural modifications. which were then characterized for dual enzyme inhibitors for these two types of enzymes (Cyclooxygenase-½ (COX-½) and 5-lipoxygenase (5-LOX) )

Nimesulide is available in various forms like powder/granules, gel, and suppositories.

Clinically it has proven that it supports a particularly good profile in terms of gastrointestinal tolerability.

Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea.

As for other NSAIDs the use of Nimesulide preffered for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea. The efficacy of Nimesulide was consistently superior to placebo with its particularly rapid onset action.

Nimesulide Pill

Nimesulide Pill

A non-steroidal anti-inflammatory most prescribed drug - Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.

This trademark also has several products by the brand name of Nimulide, Nise.

Popular NSAID drug Nimesulide is available in various forms including tablets, suppositories, soluble powders, and topical gels.

Apart from its anti inflammatory it’s also an analgesic and antipyretic in action, and it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

The drug is recommended to use for the age above 12 years and women ought to use the drug .

Nimesulide tablet chemical formula

Nimesulide, a wide prescribed medication analgesic drug belongs to BCS category II and exhibit low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a selective Cox-2 anti-inflammatory drug drug. This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatorydrug. It belongs to selective COX-2inhibitors, with a potent analgesic activity.

it’s indicated as second line treatment for acute pain, symptomatic treatment of painful degenerative joint disease and first dysmenorrhoea.

It’s conjointly used for the treatment of skin-tone, Heart diseases and dry skin.

Features include :

• Fascinating results
• Useful and helpful
• No facet effects
• Quick and fast effects

Usage of Nimesulide 100mg- pill :

• Analgesic and antipyretic.
• Rheumatic inflammatory disease, degenerative joint disease, alternative chronic joint disorders treatment
• Musculo skeletal disorders treatment
• Thrombophlebitis.
• Improves skintone
• Heart Diseases
• Dry Skin
• Cancer treatment

Nimesulide formulation

Nimesulide, a wide endorsed medicine pain relieving drug fits in with BCS classification II and show low and variable oral bioavailability. 

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compund, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatorydrug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.

its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.

It's conjointly utilized for the treatment of skin-tone, Heart illnesses and dry skin.

Nimesulide tablet features incorporate :

• Fast results
• Helpful and supportive
• No feature impacts
• Fast and quick effects

Use of Nimesulide 100mg- pill :

• Pain relieving and antipyretic.
• Rheumatic inflammatory sickness, degenerative joint ailment, elective perpetual joint issue treatment
• Musculo skeletal issue treatment
• Thrombophlebitis.
• Enhances skintone
• Heart Diseases
• Dry Skin
• Malignancy treatment
•