Wednesday, June 25, 2014
Nimesulide for acute pain and Primary dysmennorhea
Nimesuilde is a pain killer Non-steroidal medicinal drug (NSAIDs) with a complex mode of action which is the best prescribed drug for treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.
Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of Nimesulide in comparison to placebo.
In the clinical studies the efficacy of nimesulide was consistently superior to placebo, to that observed for the reference drugs, with a particularly fast onset of the analgesic action.
The rapid analgesic activity shows reductions for the pain within 15 minutes from drug intake.
The drug is available in a variety of forms such as tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel. It’s also available with various brands like Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.
Tuesday, June 24, 2014
Nimesulide Tablet
Nimesulide drug is a prescribed non-steroidal anti-inflammatory medication (NSAID) developed by Helsinn Healthcare with a multifactorial mode of action.
Nimesulide is indicated for the treatment of acute pain and primary dysmenorrhoea.
Nimesulide has superior canal safety as compared to other NSAIDs. Food, gender and advanced age have negligible effects on Nimesulide pharmacokinetics.
It is available in a very form of forms like tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel.
Nimesulide's therapeutic value in effectively and rapidly controlling inflammation and pain is supported by vital clinical evidence.
The prescription of a drug is suitable when the benefit is able to provide to a particular patient outweigh the risks associated with its use. A careful analysis of individual risk factors is therefore of crucial importance.
The maximum duration and dose of a treatment course with Nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.
Nimesulide patent gel Nimulid for Acute pain
A brand from Nimesulide Transdermal Gel, reffered as a Nimulid Transgel within which the composition contains 10mg of nimsulide in each gram of Nimulid.
Nimesulide gel preparations for localized topical application are indicated for the treatment of symptomatic relief of pain associated with sprains and acute traumatic tendinitis.
Nimullid Transgel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
The dose needed to be applied is three to four times per day depending on the dimension of the affected size and response. Medicalcare ought to be reviewed after 4 weeks.
In addition to medicament activity of Nimulid Transgel is also evaluated for primary skin irritation, eye irritation and photo toxicity in rabbits.
Nimulid Transgel doesn’t cause allergic manifestation, reddening etc.
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