Nimesulide Drug Information

Nimesulide medication developed by Helsinn Healthcare is a non-steroidal anti-inflammatory drug, indicated for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

Nimesulide tablets are authorised in a number of Member States. They are only available with a prescription.

It also used for the treatment of

• Skin Tone
• Heart Disease
• Dry Skin

It posses anti-inflammatory and analgesic properties. it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

Nimesulide is also available in the form of dissolving tablets, granules for oral suspension, and Gel. The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous environment.

The Nimesulide Tablets are highly effective in reducing pain, inflammation and also helps in better penetration of the antibiotics.

Nise tablet 100mg for pain treatment

Nise (100 mg) – Tablet, contains Generic Medicine Nimesulide- 100 mg. “Nise” tablet is a trademark for the drug “Nimesulide” which is a non-steroidal anti-inflammatory drug (NSAID).

Nise tablet has great analgesic and antipyretic properties which is nothing but relief from pain and reduction of body temperature.

Nise tablets is used in the treatment of acute pain, symptomatic relief of osteoarthritis(degradation of joints) and primary dysmenorrhoea (severe pain during menstruation) in females over the age of 12.

Usage of Nise (100 mg)- Nimesulide- Tablet

• Analgesic and antipyretic.
• Rheumatoid arthritis, osteoarthritis, other degenerative joint disorders.
• Musculo skeletal disorders.
• Thrombophlebitis.

It is also available in the form of Gel. Nise Gel (Nimesulide/Methyl Salicylate/Menthol/Capsaicin) is used topically. It is prescribed to apply to the affected area, rubbing in a thin layer of the gel 2 to 4 times every day.

Nimesulide Tablet in pain

Nimesuilde is a pain killer NSAIDs drug is the best prescribed drug for treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

Nimesulide drug has multifactorial mode of action which, gives a unique and broad action on inflammatory processes. It also has superior gastrointestinal safety as compared to other NSAIDs. It is an analgesic and antipyretic in action, other than its anti inflammatory action.

Unlike, other NSAIDs, the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group.

Apart from tablet the drug- Nimesulide is also available in various forms such as in the form of Gell, powder, and suppositories. It’s also available in various brand names of Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan e.t.c.

The Nimulid Transgel a brand from Nimesulide Transdermal Gel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

As with all drugs, therapy appropriateness when using nimesulide is of outmost importance to safeguard patient’s health and guarantee the product’s therapeutic value.

NImesulide is available in the dosage of 100 mgs for tablets, 100 mg for granules for oral suspension, 200mg for suppositories and 3% of gel. And the prescribed duration to use is for 15 days. 

Nimesulide Tablets Purpose

The main purpose of using Nimesulide 

• To treat acute pain 
• To treat osteoarthritis 
• To treat primary dysmenorrhoea in adolescents and adults above 12 years old.
• Increasing Energy
• Improving Skin Tone
• Heart Disease
• Dry Skin
• And are non-FDA reviewed or approved, natural alternatives, to use for , Heart Disease, and Dry Skin.

Nimesulide is a non-selective non-steroidal anti-inflammatory drug (NSAID) used for the treatment of Acute pain which, is a short-term pain, painful osteoarthritis (swelling in the joints), primary dysmenorrhoea (period pains). 

Medicines containing nimesulide have been available since 1985 and are authorised in a number of Member States. They are only available with a prescription.

  
Nimesulide drug is also known as nice tablet. It has superior gastrointestinal safety

Nimesulide Drugbank

The most prescribed Non-steroidal Anti-inflammatory pain killer drug- Nimesulide was launched in Italy by Helsinn Healthcare and is presently available in more than 50 countries worldwide with different trademarks.

Nimesulide tablet is used for treating acute pain and primary dysmenorrhoea and for the treatment of Joint Pains. he use of Nimesulide is preffered for the shortest duration necessary to control symptoms in patients

The maximum duration and dosage required to use is 15 days and 100 mg twice a day. It is available in different forms like tablet, capsule and gel, suppositories etc.

Nimesulide is a COX-2 selective tablet which posses anti-inflammatory and analgesic properties. it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

Nimesulide is available with different brands such as Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan e.t.c

Solubility of Nimesulide in Organic Solvents

NSAID drug Nimesulide has proven benefits in the treatment of Acute (short term) pain, Painful osteoarthritis (Swelling in the joints) and Primary dysmennorhea (Period Pains).

Nimesulide is available in various forms like Nimesulide Tablets, Nimesulide Powder, Nimesulide Gel, suppositories etc.

Nimesulide is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).

Nimesulide is an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity.

The prescription of a drug is appropriate when the benefit it is able to provide to a specific patient outweigh the risks associated with its use. A careful evaluation of individual risk factors is therefore of crucial importance.

As for other NSAIDs the use of Nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea.

Forms of Nimesulide Tablet

Nimesuilde is a pain killer NSAIDs drug is the best prescribed drug for treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

Nimesulide drug was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide with different trademarks.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

It has superior gastrointestinal safety as compared to other NSAIDs. It is an analgesic and antipyretic in action, other than its anti inflammatory action.

Unlike, other NSAIDs, the chemical structure of Nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group.

Apart from tablet the drug- Nimesulide is also available in various forms such as in the form of Gell, powder, and suppositories. It’s also available in various brand names of Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan e.t.c.

The Nimulid Transgel a brand from Nimesulide Transdermal Gel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

As with all drugs, therapy appropriateness when using Nimesulide is of out most importance to safeguard patient’s health and guarantee the product’s therapeutic value.

Nimesulide is available in the dosage of 100 mg for tablets, 100 mg for granules for oral suspension, 200mg for suppositories and 3% of gel. And the prescribed duration to use is for 15 days. 

Nimesulide 100mg dosage

An NSAID agent- Nimesulide is widely used in the treatment of variety of painful inflammatory conditions including those associated with osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders.

The most prescribed Nimesulide drug- was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide with different trademarks.

The maximum duration and dose of a treatment course with Nimesulide medicine is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity. It also preffered to use for the age above 12.

ts anti-inflammatory, analgesic and antipyretic activities have been demonstrated in several widely used animal experimental models.

Comparison of Suspension Composition of Nimesulide

Nimesulide is a non-steroidal anti-inflammatory agent that is widely used in the treatment of inflammatory pain.The efficacy and tolerability of nimesulide was consistently superior to placebo.

Nimesulide tablet undergoes extensive biotransformation and has a relatively rapid onset of action, with meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.

The drug belongs to the class II of Biopharmaceutical Classification System (low solubility, high permeability) and therefore, absorption of this drug is limited by its dissolution.

Unlike, other NSAIDs, the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group.

Nimesulide is indicated in the treatment of a variety of painful inflammatory conditions including those associated with osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders, dental surgery, bursitis/tendonitis, thrombophlebitis, pharyngitis and gynaecological disorders.

nimesulide 100mg drug interactions

Nimesulide is a leading NSAID’S drug with anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile.

Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .

Nimesulide Tablet shows the result from pain within 15min from the drug intake

Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg. Nimesulide is preffered for the shortest duration to minimize the risk of hepatotoxicity.

NImesulide tablet has a properties of analgesic (pain relief)and antipyretic (reduction of body temperature) 

The use of nimesulide in children under the age of 12 is contraindicated. Continuous use of nimesulide (more than 15 days) can cause the following side effects:
Diarrhea
Vomiting
Skin rash
Dizziness
Bitterness in mouth.

Nimesulide Actions and Uses

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor. Which has become a leading NSAID in over 50 countries worldwide for the treatment of post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness. Nimesulide is a multi-factorial drug in controlling inflammation and pain. The adverse reaction profile of nimesulide is, in general, like that of other NSAIDs. It does, however, have relatively low occurrence of gastro-intestinal (GI) side effects. As for other NSAIDs the use of Nimesulide is preffered for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea. Nimesulide is available in the form of gel, powder, capsules and tablets. Nimesulide also improves the skin tone and to increase in energy levels. Food, gender and advanced age have negligible effects on Nimesulide pharmacokinetics

Nimsulide mechanism of action for pain relief

Nimesulide drug was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide with different trademarks. Nimesuilde is a pain killer NSAIDs drug is the best prescribed drug for treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease Its multifactorial mode of action gives it a unique and broad action on inflammatory processes. It has superior gastrointestinal safety as compared to other NSAIDs. It is an analgesic and antipyretic in action, other than its anti inflammatory action." Nimesulide tablet shows pain relief from acute pain within 15 minutes from the drug intake.

Nimesulide 100mg tablet and its efficacy

Nimesulide is a anti-inflammatory agent with analgesic, antipyretic properties to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea. As for other NSAIDs the use of nimesulide is recommended for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea. It has low gastro-intestinal and renal toxicity. Nimesulide is available in the form of tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel. Nimesulide shows the instant pain relief from acute pain (short-term pain)within 15 minitues of drug intake The use of nimesulide in children under the age of 12 is contraindicated. Continuous use of nimesulide (more than 15 days) can cause the following side effects: Diarrhea Vomiting Skin rash Dizziness Bitterness in mouth.