Nimesulide Drug Composition

Nimesulide, a wide proposed drug pain relieving medication has a place with sulfonanilide class II and show low and variable oral bioavailability. Nimesulide tablets is generally utilized in inflammatory pain.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) is a particular Cox-2 calming medication. This intensify, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a particular non-steroidal mitigating medication.

It groups antihistaminic, pain relieving and antipyretic properties.

Nimesulide tablet experiences extensive biotransformation and has a generally fast onset of activity, with significant diminishments in agony and irritation saw inside 15 minutes from medication consumption.

Nimesulide is likewise being broadly utilized for anticancer and antiviral operators, and dental surgery.

Nimesulide Drug Composition

Nimesulide, a wide recommended medication analgesic drug belongs to sulfonanilide class II and exhibit low and variable oral bioavailability.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) is a selective Cox-2 anti-inflammatory drug. This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It posses antihistaminic, analgesic and antipyretic properties.

NImesulide medication is used in the treatment for acute pain, symptomatic treatment of painful degenerative joint disease and first dysmenorrhoea.

It’s conjointly used for the treatment of skin-tone, Heart diseases, Cancer and dry skin. It likewise gives Quick and quick impacts with its rapid pain relief. It is also used for increasing energy

Comparison of Suspension Composition of Nimesulide

Nimesulide is a non-steroidal anti-inflammatory agent that is widely used in the treatment of inflammatory pain.The efficacy and tolerability of nimesulide was consistently superior to placebo.

Nimesulide tablet undergoes extensive biotransformation and has a relatively rapid onset of action, with meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.

The drug belongs to the class II of Biopharmaceutical Classification System (low solubility, high permeability) and therefore, absorption of this drug is limited by its dissolution.

Unlike, other NSAIDs, the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group.

Nimesulide is indicated in the treatment of a variety of painful inflammatory conditions including those associated with osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders, dental surgery, bursitis/tendonitis, thrombophlebitis, pharyngitis and gynaecological disorders.