Nimesulide Pill

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.
Major interactions involving interference with drug metabolism have not been described with Nimesulide.
Nimesulide is a leading NSAID’S srug with analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile.
Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .
Nimesulide Tablet shows the result from pain within 15min from the drug intake
Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg
Nimesulide is preffered for the shortest duration to minimize the risk of hepatotoxicity.

A non-steroidal anti-inflammatory most prescribed drug – Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.

This trademark also has several products by the brand name of Nimulid, Nise.

Popular NSAID drug Nimesulide is available in various forms including tablets, suppositories, soluble powders, and topical gels.

Apart from its anti inflammatory it’s also an analgesic and antipyretic in action, and it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

The drug is recommended to use for the age above 12 years and women ought to use the drug with caution throughout lactation.

Nimesulide Tablet Dosage

The main purpose of Nimesulide tablets is for the treatment of painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

The usual dose is 100mg twice a day.
Children: 5mg/kg of body weight in 2 or 3 divided doses.

The minimum effective dose should be used for the shortest duration to reduce the undesirable effects.

The maximum duration of a treatment course with Nimesulide is 15 days.

Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.

Adults:
100mg bid after meal.

Elderly:
In elderly patients there is no need to reduce the daily dosage

Children (< 12 years):
Nimesulide 100mg Tablets/granules is contraindicated in these patients.

Adolescents (from 12 to 18 years):
on the basis of the kinetic profile in adults and on the pharmacodynamic characteristics of nimesulide, no dosage adjustment in these patients is necessary.

Oral dosage form prescribed for the shortest duration

In adults:100 mg In children: 5 mg/kg/day in 2 or 3 divided doses.

Nimesulide has superior gastrointestinal safety as compared to other NSAIDs. Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Nimesulide tablet prevents cancer by inhibiting the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms. It is also used for dry skin, to improve skin-tone,and to increase energy.

Nimesulide treatment also brought about an immediate and significant improvement in over-all pain, exudation, oedema and headache.

Nimesulide multifactorial approach

Nimesulide was launched in Italy for the first time as Aulin and Mesulid in 1985 and is presently available in more than 50 countries worldwide in different trademarks.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.It is available in the market in various like tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

The Gel needed to be applied is three to four times per day depending on the dimension of the affected size and response. Medicalcare ought to be reviewed after 4 weeks.

Trademarks of Nimesulide include of Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan e.t.c.Nimulid Transgel is indicated for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

Nimesulide has superior gastrointestinal safety as compared to other NSAIDs with multi factorial approach for treating post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.

Nimesulide dosage to reduce pain

Nimesulide treats post-traumatic inflammation, acute musculoskeletal disorders and osteoarthritis (joint pains).
It is available with the dosage of 100 mg for the tablets, and 100 mg for granules for oral suspension, 200 mg for the suppositories and 3% of gel.
Nimesulide tablet is recommended for the shortest duration. The maximum duration and dose of a treatment course with nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.
Non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor – Nimesulide has multi factorial approach for the treatment of for the treatment of post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.
The maximum duration recommended to be used is 15 days and dose required for the treatment 100 mg twice a day, to minimize the risk of hepatotoxicity.

It has low gastro-intestinal and renal toxicity. with analgesic and antipyretic properties.

Nimesulide Drug Uses

• Nimesulide has less gastrointestinal adverse effects than other NSAIDs.
• It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory.
• Nimesulide is also safe in sensitive asthmatic patients.
• It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
• Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities.
  Nimesulide does not have significant gastroduodenal side effects.
  It has superior gastrointestinal safety as compared to other NSAIDs.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.
  It has proven benefits in the treatment of Acute (short term) pain, Painful osteoarthritis (Swelling in the joints) and Primary dysmennorhea ( Period Pains).
  To treat acute pain
  To treat osteoarthritis
  To treat primary dysmenorrhoea in adolescents and adults above 12 years old.
  Increasing Energy
  Improving Skin Tone.

Nimesulide uses

NSAIDs drug Nimesulide has proven benefits in the treatment of Acute (short term) pain, Painful osteoarthritis (Swelling in the joints) and Primary dysmennorhea ( Period Pains)

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

The tablet has superior gastrointestinal safety as compared to other NSAIDs

Apart from Tablet NImesulide is also available in the form of powder, gel, suppositories, mouth dissolving tablets.

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which means it provides analgesic (pain-killing) and antipyretic(fever-reducing) effects. Nimesulide is mostly used for treatment of short-term pain(Acute), joint pain (osteoarthritis), period pains (Primary dysmennorhea), Chronic pains and many.

Acute Pain: starts suddenly and usually feels sharp. Broken bones, burns, or cuts are examples of acute pain. Acute pain lasts just a moment or it may last for weeks or months. Some times it may also lead to Chronic pain (long-term pain)

Eg of Chronic pains:

• Headache
• Low back pain
• Cancer pain
• Arthritis pain
• Pain caused by nerve damage

Nimesulide shows positve reaction in the treatment of several painful situations with an acute inflammatory component including primary dysmenorrhea because of the rapid onset of the analgesic action. which Nimesulide shows meaningful reductions observed within 15 minutes from drug intake.Osteoarthritis: It is most common in middle-aged and older people, and its symptoms can range from very mild to very severe it mostly affects hands and weight-bearing joints such as Knees, hips, feet and the back, but can affect almost any joint in the body.

Nimesulide Tablet Uses

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor. It has become a leading NSAID in over 50 countries worldwide.

Nimesulide tablet is used for the treatment of osteoarthritis, postoperative trauma, sports injuries, acute musculoskeletal disorders including tendonitis, tenosynovitis, sprains, strains and low back pain, ear, nose and throat disorders

Usage of Nimesulide 100mg- Tablet:

• Nimesulide has less gastrointestinal adverse effects than other NSAIDs 
• It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
• Its multifactorial mode of action gives it a unique and broad action on inflammatory. 
• Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment. 
• Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities
• Nimesulide tablet undergoes extensive biotransformation and has a relatively rapid onset of action, with meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.

Its an anti-inflammatory with analgesic and antipyretic activity. It is also has low gastro-intestinal and renal toxicity.

Nimesulide Tablet

Nimesulide drug is a prescribed non-steroidal anti-inflammatory medication (NSAID) developed by Helsinn Healthcare with a multifactorial mode of action. Nimesulide is indicated for the treatment of acute pain and primary dysmenorrhoea. Nimesulide has superior canal safety as compared to other NSAIDs. Food, gender and advanced age have negligible effects on Nimesulide pharmacokinetics. It is available in a very form of forms like tablets, powder for dissolution in water, suppositories, mouth dissolving tablets and topical gel. Nimesulide's therapeutic value in effectively and rapidly controlling inflammation and pain is supported by vital clinical evidence. The prescription of a drug is suitable when the benefit is able to provide to a particular patient outweigh the risks associated with its use. A careful analysis of individual risk factors is therefore of crucial importance. The maximum duration and dose of a treatment course with Nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.