Tuesday, May 20, 2014

Nimesulide and Paracetamol

The efficacy and tolerability of nimesulide 100mg were compared with those of paracetamol in a nonblind randomised study that recruited 110 children (64 males, 46 females; aged 3 to 6 years) with inflammation of the upper respiratory tract and fever. Nimesulide suspension (1.5 mg/kg 3 times daily) or paracetamol syrup (10 mg/kg 4 times daily) were administered orally until fever resolved. Body temperature was recorded and local pain and general discomfort assessed. Three patients treated with nimesulide and 6 patients treated with paracetamol withdrew from the study as a result of adverse events, and 1 paracetamol-treated patient discontinued because of a requirement for therapy with steroids. Nimesulide was as effective as paracetamol in reducing fever, local pain, and general discomfort. Nimesulide therefore appears to be at least as effective as paracetamol in terms of antipyretic and anti-inflammatory activity in children with inflammation of the upper respiratory tract and fever.

5 comments:

  1. Nimesulide worked effectively for me.

    ReplyDelete
  2. Heard it is Banned. Is it True?

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  3. Nimesulide is useful as pain killer. Here is an actual incident supporting this point of view.
    MUMBAI: In mid-August, an 11-month-old boy from Ghansoli in Navi Mumbai was brought to paediatrician Vijay N Yewale’s clinic in Thane with severe dehydration and breathlessness.

    The child was diagnosed with pneumonia and had to be hospitalised. While pneumonia is quite common, in this case, a highly potent drug called ‘Nimesulide’ was given to control the fever. The drug immediately brought the fever under control.

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  4. This my person experience with nimesulide drug:- usually i suppose to work for night shift and every one know body pain is common pain for such person. i used to take nimesulide tablet for pain relief. I am using this drug from last 3 years with recommended dose, up til now i din't experience any side effects.

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  5. This my person experience with nimesulide drug:- usually i suppose to work for night shift and every one know body pain is common pain for such person. i used to take nimesulide tablet for pain relief. I am using this drug from last 3 years with recommended dose, up til now i din't experience any side effects.

    ReplyDelete