Nimesulide is a non-steroidal anti-inflammatory agent that is generally
utilized as a part of the treatment of inflammatory torment which
hinders the protein cyclooxygenase-2 (COX-2) and has better
gastro-intestinal mediocrity in addition to different NSAIDs in its
class.
Its approved signs are the treatment of intense torment, the symptomatic treatment of osteoarthritis and essential dysmenorrhoea, sports wounds and so on.
A mixed bag of new nimesulide subsidiaries were synthesized through incorporation of a 5-LOX pharmacophore into Nimesulide took after with some structural changes. which were then portrayed for double protein inhibitors for these two sorts of enzymes (Cyclooxygenase-½ (COX-½) and 5-lipoxygenase (5-LOX) )
Clinically it has demonstrated that it supports an especially good profile as far as gastrointestinal tolerability
Its approved signs are the treatment of intense torment, the symptomatic treatment of osteoarthritis and essential dysmenorrhoea, sports wounds and so on.
A mixed bag of new nimesulide subsidiaries were synthesized through incorporation of a 5-LOX pharmacophore into Nimesulide took after with some structural changes. which were then portrayed for double protein inhibitors for these two sorts of enzymes (Cyclooxygenase-½ (COX-½) and 5-lipoxygenase (5-LOX) )
Clinically it has demonstrated that it supports an especially good profile as far as gastrointestinal tolerability
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