Nimesulide is used in giving relief from acute pain associated with rheumatoid arthritis, osteoarthritis and primary dysmenorrhoea in adolescents and adults.
The drug is also an effective antipyretic and used to treat headaches and flu. It is also used in treating inflammatory conditions in humans and pain caused by arthritis or severe injury.
Nimesulide is a popular NSAID and available in various forms including tablets, suppositories, water-soluble powders, and topical gels.
Working of Nimesulide
It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation
Nimesulide Dosage
Adults: 100 mg twice daily
Children: 5mg/kg of body weight in 2 or 3 divided doses.
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