Nimesulide tablet dissolution

The most commonly prescribed NSAID's drug - Nimesulide for the treatment of various inflammatory conditions such as tonsillitis, pharyngitis, stomatitis, rheumatoid arthritis, osteoarthritis, low back pain etc.,

The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous environment.

Nimesulide is also well tolerated by asthmatic patients

Nimesulide is available in various forms like Nimesulide Tablets, Nimesulide Powder, Nimesulide Gel, suppositories etc.

Nimesulide is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).

Nimesulide is an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity.

The prescription of a drug is appropriate when the benefit it is able to provide to a specific patient outweigh the risks associated with its use. A careful evaluation of individual risk factors is therefore of crucial importance.

As for different NSAIDs the employment of Nimesulide is usually recommended for the shortest length necessary to regulate symptoms in patients with acute pain or primary dysmenorrhoea

The prescription of a drug is acceptable once the profit it’s ready to offer to a selected patient outweigh the risks related to its use. A careful analysis of individual risk factors is so of crucial importance.

As for different NSAIDs the employment of Nimesulide is usually recommended for the shortest length necessary to regulate symptoms in patients with acute pain or primary dysmenorrhoea.

Nimesulide dosage

Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-2 an enzyme responsible for inflammation & pain.

The nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.

This medication is for the most part used as an issue of the treatment of inflammatory torment and also used for postoperative trauma, sports injuries, acute musculoskeletal disorders.

Nimesulide have pain relieving and antipyretic properties which, specially restrains the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal bearableness in addition to different Nsaids in its class.

Dosage:

The usual dose is 100mg twice a day.
Children: 5mg/kg of body weight in 2 or 3 divided doses.

The minimum effective dose should be used for the shortest duration to reduce the undesirable effects.

The maximum duration of a treatment course with Nimesulide is 15 days.

Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.