Nimesulide Structure and its Uses

Nimesulide Structure and its Uses

Nimesulide is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It is available in more than 50 countries worldwide.

Features: 

• Amongst most effective yet gastro friendly 
• Non steroidal anti inflammatory drug (NSAID) 
• Nimesulide targets COX-2 an enzyme responsible for inflammation & pain. 

Uses of Nimesulide:

• Nimesulide tablet has excellent gastrointestinal safety in comparison to other medication. 
• Rapid onset of action within 15 minutes 
• Rapidly relieves pain in arthritis

Indications:

• acute pain;
• primary dysmenorrhoea.

Nimesulide Structure and its Uses

Nimesulide is generally utilized as a part of the treatment of inflammatory torment which hinders the protein cyclooxygenase-2 (COX-2) and has better gastro-intestinal mediocrity in addition to different NSAIDs in its class.

Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) This compound, a by-product of p-nitrophenyl methane series sulfa, is structurally a singular non-steroidal anti-inflammatory drug.

It is available in more than 50 countries worldwide.

Features: 

• Amongst most effective yet gastro friendly 
• Non steroidal anti inflammatory drug (NSAID) 
• Nimesulide targets COX-2 an enzyme responsible for inflammation & pain. 

Uses of Nimesulide:

• Nimesulide tablet has excellent gastrointestinal safety in comparison to other medication. 
• Rapid onset of action within 15 minutes 
• Rapidly relieves pain in arthritisIndications:
  • acute pain;
  • primary dysmenorrhoea.

Nimesulide Drugbank

Nimesulide Drugbank

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties which, preferentially inhibits the enzyme cyclooxygenase-2 (COX-2) and has better gastro-intestinal tolerability among other NSAIDs in its class

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea, sports injuries etc.

It is used for treatment of all types of pains resulting from sports injury, depression etc.

Nimesulide dose should be taken by prescription of physician and doctor which will help to take proper dose for good result.

Pharmacology: Food, gender and advanced age have negligible effects on Nimesulide pharmacokinetics.

Brands:

Nimesulide is accessible in worldwide among 50 nations with different brands like Sulide, Nimalox, Nimesil, Nimulid, Nicip, Nimcap, Nise, Sulidene and Zolan.

Nimesulide 100mg

Nimesulide Tablet 100mg

The best prescribed Nimesulide tablet is used for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

Forms: A variety of Nimesulide forms are available in the market like in the form of tablets and syrup for oral administration and gels for topical application.

Nimesulide 100mg Therapeutic indications:

• Treatment of acute pain
• Symptomatic treatment of painful osteoarthritis
• Primary dysmenorrhoea.

Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.

Absorption:
Well absorbed from GI tract following oral admin. Peak plasma levels:1-3 hours. With bid admin of 100 mg, steady-state is achieved within 24-36 hours.

Nimesulide 100mg Uses:

• Analgesic and antipyretic.
• Rheumatoid arthritis, osteoarthritis, other degenerative joint disorders.
• Musculo skeletal disorders.
• Thrombophlebitis.

Nimesulide is commercially available in Europe as tablets (100 mg), granules for oral suspension (100 mg), suppositories (200 mg) and gel (3%).

Nimesulide Combination

Monday, November 2, 2015

Nimesulide Combination

The generic Nimesulide combination is manufactured by 399 companies and has nearly 522 Brands of Generics of Nimesulide.

Nimesulide is a Non steroidal anti inflammatory drug (NSAID) and targets COX-2 an enzyme responsible for inflammation & pain.

The Nimesulide is preferably used in the composition in an amount of 0.1-5% by weight, more preferably in an amount of 0.1-3% by weight, most preferably in an amount of around 1 % by weight of the composition.

Some of brands of Nimesulide are:

• Nepar – Nimuselide 100 mg + Paracetamol 500 mg
• Nimular Plus – Nimesulide, Acetaminophen
• Nipar (100 mg) – Nimesulide, Paracetamol
• Abinim-P – Nimesulide 100 mg, paracetamol 500 mg.Nimesulide is distributed world-wide through a network of selected international partners.

Nimesulide is mainly used for the treatment of:

• Back Pain
• Dysmenorrhea
• Osteoarthritis
• Rheumatoid Arthritis

Nimesulide is always recommended to use under a licensed physician supervision

Nimesulide Tablet Indication

Nimesulide medication is a non-steroidal medicinal drug, prescribed for painful inflammatory conditions, back pain, hurting, operative pain, arthritis, and fever.

The various inflammatory conditions like inflammation, sore throat, stomatitis, autoimmune disease, arthritis, low back pain etc., may be treated by Nimesulide pill.

It has a complex mode of action and is characterised by a quick onset of action.

The therapeutic effects of Nimesulide area unit the results of its complete mode of action that targets variety of key mediators of the inflammatory method such as: Cox-2 mediate prostaglandins, free radicals, chemical action enzymes and aminoalkane. Clinical proof is accessible to support a very smart profile in terms of gi tolerability.

It is used for treatment of every type of pains ensuing from sports injury, depression etc.

Nimesulide is indicated in painful inflammatory conditions associated with musculoskeletal system, dysmenorrhoea, Thrombophlebitis, dental pain and in ENT inflammation.
Tablets or Granules: 100 mg twice a day after meals400 mg nimesulide-beta-cyclodextrin Tablets or Granules: 400 mg (= 100 mg nimesulide)twice a day after mealsSuppositories: 200 mg twice a day
Features:

Desirable resultsHelpful and beneficialNo side effectsFast and quick effects Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required byt the clinical situation.

Nimesulide Pill

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.
Major interactions involving interference with drug metabolism have not been described with Nimesulide.
Nimesulide is a leading NSAID’S srug with analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile.
Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .
Nimesulide Tablet shows the result from pain within 15min from the drug intake
Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg
Nimesulide is preffered for the shortest duration to minimize the risk of hepatotoxicity.

A non-steroidal anti-inflammatory most prescribed drug – Nimesulide that contains dose of 100mg and it’s used for treating acute (short-term) pain, painful osteoarthritis (swelling in the joints), and Primary dysmennorhea (Period Pains).

Nimesuilde is first launched in 1985and currently it’s on the market in worldwide of over 50 countries as orginal product with the trademarks of Nise, Nimopen-MP, Nic-Spas, Nimulid, Nicip, e.t.c.

This trademark also has several products by the brand name of Nimulid, Nise.

Popular NSAID drug Nimesulide is available in various forms including tablets, suppositories, soluble powders, and topical gels.

Apart from its anti inflammatory it’s also an analgesic and antipyretic in action, and it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

The drug is recommended to use for the age above 12 years and women ought to use the drug with caution throughout lactation.