Nimesulide is a prescription non-steroidal anti-inflammatory drug with a multifactorial mode of action for the treatment of for post-traumatic inflammation, acute musculoskeletal disorders including sprains, strains, tendinitis, tenosynovitis, low back pain, periarthritis (shoulder pain) and osteoarthritis (joint pains), stiffness.
Its multifactorial mode of action gives it a unique and broad action on inflammatory processes. It undergoes extensive biotransformation.
Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.
In these studies, the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic action.
This rapid onset of analgesic action shows meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.
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