Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory pain killer drug(NSAID) prescribed for treatment of acute pain, Primary dysmennorhea and degenerative joint disease.
This medicine has potent analgesic, anti pyretic and anti-inflammatory activity on oral & rectal administration.
Nimesulide BP 100mg prevents the release of prostaglandins which is responsible for inflammation, pain & fever.
Nimesulide is a selective inhibitor of prostaglandin synthesis but appears to exert its therapeutic effect by a variety of other mechanisms like inhibition of platelet-activating factor (PAF), tumour necrosis factor-alpha (TNF alpha,) Proteinase & histamine etc.
Nimesulide is Indicated in reducing pain, fever and inflammatory symptoms of:
- Chronic arthritis
- Osteo arthritis
- Otorhinolary diseases
- Soft tissues and oral cavity inflammation
- Dysmenorrhoea
- Thrombosis
- Urogenital disease
- Postoperative pain states
- Sports injuries
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