There
are more than 100 types of cancer, including breast cancer, skin
cancer, lung cancer, colon cancer, prostate cancer, and lymphoma.
Symptoms vary depending on the type.
A
series of new nimesulide analogs were synthesized based on the
structure–function analysis generated previously. It displayed very
potent anti-cancer activity.
significantly
suppresses the growth of multiple cancer. By uing Nimesulide the
sizes of the colon carcinomas were also decreased.
Pharmacokinetic
studies demonstrate the good bioavailability of the compound. A set
of non-COX-2 active Nimesulide anti-cancer derivatives were
synthesized. It works as a good lead compound for anti-cancer drug
development.
Cyclooxygenase-2
(COX-2) inhibitor Nimesulide inhibits the proliferation of various
types of cancer cells mainly via COX-2 independent mechanisms, which
makes it a good lead compound for anti-cancer drug development.
Cancer,
also known as a malignant tumour or malignant neoplasm, is a group of
diseases involving abnormal cell growth with the potential to invade
or spread to other parts of the body. Cyclooxygenase-2 (COX-2)
inhibitor Nimesulide inhibits the proliferation of various types of
cancer cells mainly via COX-2 independent mechanisms, which makes it
a good lead compound for anti-cancer drug development.
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