Nimesulide BP

Nimesulide BP 100mg

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory pain killer drug(NSAID) prescribed for treatment of acute pain, Primary dysmennorhea and degenerative joint disease.

This medicine has potent analgesic, anti pyretic and anti-inflammatory activity on oral & rectal administration.

Nimesulide BP 100mg prevents the release of prostaglandins which is responsible for inflammation, pain & fever.

Nimesulide is a selective inhibitor of prostaglandin synthesis but appears to exert its therapeutic effect by a variety of other mechanisms like inhibition of platelet-activating factor (PAF), tumour necrosis factor-alpha (TNF alpha,) Proteinase & histamine etc.

Nimesulide is Indicated in reducing pain, fever and inflammatory symptoms of:

• Chronic arthritis
• Osteo arthritis
• Otorhinolary diseases
• Soft tissues and oral cavity inflammation
• Dysmenorrhoea
• Thrombosis
• Urogenital disease
• Postoperative pain states
• Sports injuries

Nimesulide tablet for Bp

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory pain killer drug(NSAID) prescribed for treatment of acute pain, Primary dysmennorhea and degenerative joint disease.

This medicine has potent analgesic, anti pyretic and anti-inflammatory activity on oral & rectal administration.

Nimesulide BP 100mg prevents the release of prostaglandins which is responsible for inflammation, pain & fever.

Nimesulide is a selective inhibitor of prostaglandin synthesis but appears to exert its therapeutic effect by a variety of other mechanisms like inhibition of platelet-activating factor (PAF), tumour necrosis factor-alpha (TNF alpha,) Proteinase & histamine etc.

Nimesulide is Indicated in reducing pain, fever and inflammatory symptoms of:

• Chronic arthritis
• Osteo arthritis
• Otorhinolary diseases
• Soft tissues and oral cavity inflammation
• Dysmenorrhoea
• Thrombosis
• Urogenital disease
• Postoperative pain states
• Sports injuries

Nimesulide Tablet for Cancer Treatment

There are more than 100 types of cancer, including breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma. Symptoms vary depending on the type.

A series of new nimesulide analogs were synthesized based on the structure–function analysis generated previously. It displayed very potent anti-cancer activity.

significantly suppresses the growth of multiple cancer. By uing Nimesulide the sizes of the colon carcinomas were also decreased.

Pharmacokinetic studies demonstrate the good bioavailability of the compound. A set of non-COX-2 active Nimesulide anti-cancer derivatives were synthesized. It works as a good lead compound for anti-cancer drug development.

Cyclooxygenase-2 (COX-2) inhibitor Nimesulide inhibits the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms, which makes it a good lead compound for anti-cancer drug development.

Cancer, also known as a malignant tumour or malignant neoplasm, is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Cyclooxygenase-2 (COX-2) inhibitor Nimesulide inhibits the proliferation of various types of cancer cells mainly via COX-2 independent mechanisms, which makes it a good lead compound for anti-cancer drug development.

Nimesulide for rapid pain relief

Non-steroidal anti-inflammatory pain relief drug Nimesulide is prescribed for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.

The drug is developed by Helsinn Healthcare. Medicines containing Nimesulide are on the market since 1985 and are authorised in a number of Member States.

Nimesulide also improves the skin tone and to increase in energy levels. Food, gender and advanced age have negligible effects on Nimesulide pharmacokinetics.

Its multifactorial mode of action gives it a unique and broad action on inflammatory processes.

Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic action.

This rapid onset of analgesic action shows meaningful reductions in pain and inflammation observed within 15 minutes from drug intake.

Unlike, other NSAIDs, the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group.

As with all drugs, therapy appropriateness when using nimesulide is of outmost importance to safeguard patient’s health and guarantee the product’s therapeutic value.

Nimesulide Tablet Synthesis

Nimesulide, a COX-2 selective drug, possesses anti-inflammatory and analgesic properties. Moreover, it has low gastro-intestinal and renal toxicity.

Its main purpose is to treat acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea .

As for other NSAIDs the use of Nimesulide is preffered for the shortest duration necessary to control symptoms in patients with acute pain or primary dysmenorrhoea. The efficacy of Nimesulide was consistently superior to placebo with its particularly rapid onset action.

The maximum duration and dose of a treatment course with nimesulide is 15 days, 100 mg twice a day, to minimize the risk of hepatotoxicity.

Nimesulide Tablet shows the result from pain within 15min from the drug intake

Nimesulide is available in the from of tablet, capsule and gel with the dosage of 100mg

Nimesulide for instant pain relief

Pain relief drug nimesulide which shows the instant pain relief from acute pain (short-term pain)within 15 minitues of drug intake for the acute pain.

Nimesulide is a prescription-only drug and must be prescribed by a licensed physician after careful evaluation of the patient’s characteristics and needs.

It must be used under supervision by a doctor in accordance with the approved indications and in compliance with the recommendations .The overall safety profile of nimesulide is in line with that of all other NSAIDs. As with all drugs, it must be used in the most appropriate way to guarantee its best therapeutic value.

Clinical studies have been carried out in a wide variety of acute inflammatory and painful conditions with the aim of evaluating the analgesic activity of nimesulide in comparison to placebo and to some of the most common NSAIDs.

In these studies, it is observed that the efficacy of nimesulide was consistently superior to placebo with a particularly fast onset of the analgesic in action.

Nimesulide Granules

Nimesulide Granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea.

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
Active ingredients: nimodipine. Indication: nimesulide granules is non-steroidal anti-inflammatory drugs, indicated for the treatment of juvenile chronic arthritis, postoperative pain, acute pain after trauma and primary dysmenorrhea. Packaging: 1g / sack; 6, 8, 10 sacks / pack. Contact us for more information.

usage and consumption: oral, the goods only for adults only, a 50 mg to 100 mg daily twice postprandial taking. In accordance with the severity of the conditions and the needs of the patients can be increased to 0.2g, the second service.
elderly patients of the medication should strictly comply with the provisions of doctors. Doctors can reduce under appropriate in the circumstances listed above dosage.

Nimesulide has a potent Anti-Inflammatory action.It behaves as a competetive inhibitor of histamine release in-vivo and in-vitro, hence posseses antihistaminic and antiallergic properties.

Indications: Nimesulide is indicated in painful inflammatory conditions associated with musculoskeletal system, dysmenorrhoea, Thrombophlebitis, dental pain and in ENT inflammation. Absorption Well absorbed from GI tract following oral admin. Peak plasma levels:1-3 hours. With bid admin of 100 mg, steady-state is achieved within 24-36 hours.

Routes of Administration and Dosage: Oral dosage form in adults :100 mg b.i.d In children : 5 mg/kg/day in 2 or 3 divided doses.