Wednesday, November 18, 2015

Nimesulide Formulation


Nimesulide, a widely prescribed anti-inflammatory analgesic drug belongs to BCS class II and exhibit low and variable oral bioavailability.
Nimesulide (4-nitro-2-phenoxymethanesulfoanilide) may be a particular Cox-2 anti-inflammatory medication. This compound, a by-result of p-nitrophenyl methane arrangement sulfa, is structurally a solitary non-steroidal anti-inflammatory drug. It has a place with particular COX-2inhibitors, with an intense pain relieving movement.
its shown as second line treatment for  acute pain, symptomatic treatment of excruciating degenerative joint ailment and first dysmenorrhoea.
Nimesulide tablet incorporates:
  • Fast results
  • Helpful and supportive
  • No feature impacts
  • Fast and quick effects
Nimesulide Tablet Advantages:
  • Nimesulide has less gastrointestinal adverse effects than other NSAIDs
  • It has superior benefit-risk ratio to other drugs with a comparable safety and tolerability to placebo.
  • Its multifactorial mode of action gives it a unique and broad action on inflammatory.
  • Nimesulide is also safe in sensitive asthmatic patients. It is reported to be beneficial in relieving the symptoms of rhinitis, rhinopharyngitis tubaritis and seceretory otitis media with concomitant antibiotic treatment.
  • Nimesulide has potent analgesic, anti-inflammatory and antipyretic activities

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