Thursday, November 5, 2015

Nimesulide tablet dose

Nimesulide medication is a non-steroidal anti-inflammatory drug, prescribed for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.Nimesulide Dosage:

Adults:
 100 mg twice daily
Children: 5mg/kg of body weight in 2 or 3 divided doses.Nimesulide 100mg Tablets/granules should be used for the shortest possible duration, as required by the clinical situation.

Adults:
100mg bid after meal.

Elderly:
In elderly patients there is no need to reduce the daily dosageThe best prescribed Nimesulide tablet is used for the treatment of acute pain, Primary dysmennorhea and also to treat degenerative joint disease.Forms: A variety of Nimesulide forms are available in the market like in the form of tablets and syrup for oral administration and gels for topical application.Dose: Nimesulide is available with the dosage of 100 mg for tablets, 100 mg for granules for oral suspension, 200mg for suppositories and 3% of gel.Nimesulide tablets exerts less gastrointestinal adverse effects than other NSAIDs. It is available in different brands in worldwide among 50 countries.Nimesulide is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).Nimesulide transdermal gel is a well tolerated novel hydroalcoholic microcarrier based drug delivery system with penetration enhancer, indicated for a variety of conditions characterized by pain, inflammation and stiffness, such as osteoarthritis, periarthritis, post-traumatic or acute musculoskeletal disorders including tendinitis, tenosynovitis, sprains, strains and low back pain.Solubility of Nimesulide was studied using different cosolvent mixtures and various classes of non-ionic surfactant. Solubility increased drastically (>70 mg/rnl) when polyethylene glycol 300 and polyethylene glycol 400 were used as solvents.The quick dissolving tablets of Nimesulide contains superdisintegrants, that accelerates the disintegration of tablets by virtue of their ability to soak up great deal of water once exposed to binary compound surroundings.








1 comment:

  1. Nimesulide drug must be prescribed by a physician and doctor and is usually recommended for the age higher than 12 years
    The maximum period and dose required to use is 15 days of treatment course and 100mg twice a day

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