Thursday, November 26, 2015

Nimesulide drug interactions


Nimesulide is a prescribed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile.

Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults.

it’s an ethical medicine suggested to use medicine beneath authorised physician supervision.

Nimesulide is a recently developed analgesic, antipyretic and anti-inflammatory agent that differs from conventional nonsteroidal anti-inflammatory drugs both in structure and pharmacological profile. Since nimesulide may be prescribed for patients receiving concomitant medication, the propensity for drug interactions exists.
Nimesulide is also available in the form of dissolving tablets, granules for oral suspension, and Gel. The fast dissolving tablets of Nimesulide contains superdisintegrants, which accelerates the disintegration of tablets by virtue of their ability to absorb large amount of water when exposed to aqueous Environment.
Major interactions involving interference with drug metabolism have not been described with Nimesulide.
A marginal decrease in plasma theophylline levels (without changes in respiratory function tests) has been described after addition of Nimesulide to chronic theophylline therapy. Nimesulide is available in the market with the dosage of 100Mg.


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